geroprobПроблемы геронаукиProblems of Geroscience2949-47452949-4753АНО «ОСО ИТЕМ»10.37586/2949-4745-1-2024-13-21geroprob-26Research ArticleОбзорыReviewsСвязь артериальной гипертензии и ожирения с основными гериатрическими синдромамиHow Arterial Hypertension and Obesity Contribute to Geriatric SyndromesКоняеваЕ. С.KoniaevaE. S.

Коняева Екатерина Сергеевна, врач-терапевт лаборатории биомаркеров старения,

Москва.

Koniaeva Ekaterina S., MD, Laboratory of Biomarkers of Aging, 

Moscow.

panv@bk.ruhttps://orcid.org/0000-0002-3657-0676СтражескоИ. Д.StrazheskoI. D.

Стражеско Ирина Дмитриевна, д-р мед. наук, заместитель директора по трансляционной медицине; ведущий научный сотрудник отдела возраст-ассоциированных заболеваний,

Москва.

Телефон: +7(903)520-41-54

Strazhesko Irina D., MD, PhD, Deputy Director for translational medicine; Leading Researcher at the Department of Age-related diseases

Moscow.

Phone: +7(903)520-41-54

istrazhesko@gmail.comФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центрРоссияRussian Gerontology Research and Clinical Centre, Pirogov Russian National Research Medical UniversityRussian Federation202430062024011321Copyright © Коняева Е.С., Стражеско И.Д., 20242024Коняева Е.С., Стражеско И.Д.Koniaeva E.S., Strazhesko I.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geronauka.com/jour/article/view/26

Артериальная гипертензия и ожирение являются традиционными факторами сердечно-сосудистого риска. Однако их влияние на развитие и течение основных гериатрических синдромов среди лиц старше 60 лет мало изучено. Известно, что зависимость между наличием АГ или ожирения и развитием старческой астении, саркопении, когнитивных нарушений имеет непрямолинейный характер и зависит от возраста. Если наличие кардиоваскулярных факторов в пожилом возрасте является фактором риска развития гериатрических синдромов, то в старческом возрасте их влияние нивелируется или приобретает защитную роль. Немногочисленные исследования долгожителей как примеров «успешного старения» подтверждают это предположение. Также в обзоре обсуждается влияние АГ и ожирения на прогноз у лиц пожилого и старческого возраста, а также долгожителей.

Arterial hypertension and obesity are well-established cardiovascular risk factors, but their impact on major geriatric syndromes in individuals over 60 is not well understood. The association between hypertension, obesity, and the development of frailty, sarcopenia, and cognitive impairment varies depending on age. As individuals age, the impact of cardiovascular factors on geriatric syndromes decreases or becomes less significant. This hypothesis is supported by a number of studies on centenarians. The review also examines the impact of hypertension and obesity on prognosis in older individuals.

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The authors declare that there are no conflicts of interest present.