geroprobПроблемы геронаукиProblems of Geroscience2949-47452949-4753АНО «ОСО ИТЕМ»10.37586/2949-4745-2-2024-86-91geroprob-59Research ArticleОбзорыReviewsКурение и темпы старения организма: современное состояние вопросаSmoking and the rate of aging: the current state of the issuehttps://orcid.org/0000-0002-8505-1848ГиляревскийС. Р.GilyarevskyS. R.

Гиляревский Сергей Руджерович, д-р мед. наук, профессор, ведущий научный сотрудник Российского геронтологического научно-клинического центра; профессор кафедры клинической фармакологии и терапии РМАНПО

Москва

Research ID: AAN-4179-2021

Gilyarevsky Sergey R., MD, PhD, professor, senior researcher, Russian Gerontology Research and Clinical Centre; Professor at the Department of Clinical Pharmacology and Therapy

Moscow

Research ID: AAN-4179-2021

panv@bk.ruhttps://orcid.org/0000-0003-0048-268XЕруслановаК. А.EruslanovaK. A.

Ерусланова Ксения Алексеевна, канд. мед. наук, заведующая лабораторией сердечно-сосудистого старения

Москва

Телефон: +7(499)187-78-09

Eruslanova Ksenia A., MD, PhD, Head of the Laboratory of Cardiovascular Aging

Moscow

tel. +7(499)187-78-09

Eruslanova_KA@rgnkc.ruhttps://orcid.org/0000-0002-4193-688XТкачеваО. Н.TkachevaO. N.

Ткачева Ольга Николаевна, член-корреспондент РАН, д-р мед. наук, профессор, директор Российского геронтологического научно-клинического центра

Москва

Телефон: +7(499)187-64-67

Tkacheva Olga N., MD, PhD, professor, corresponding member of the Russian Academy of Sciences, Director

Moscow

tel. +7(499)187-64-67

tkacheva@rgnkc.ruРНИМУ им. Н.И. Пирогова Минздрава России, ОСП «Российский геронтологический научно-клинический центр»РоссияRussian Gerontology Research and Clinical Centre, Pirogov Russian National Research Medical UniversityRussian Federation202430062024028691Copyright © Гиляревский С.Р., Ерусланова К.А., Ткачева О.Н., 20242024Гиляревский С.Р., Ерусланова К.А., Ткачева О.Н.Gilyarevsky S.R., Eruslanova K.A., Tkacheva O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geronauka.com/jour/article/view/59

Статья представляет собой обзор, посвященный оценке влияния курения на здоровье и темпы старения в разные периоды жизни человека. В работе рассматривается связь между курением и различными маркерами старения, приводятся данные исследований менделевского типа, в ходе которых оценивали вклад генетических факторов в предрасположенность к курению и влияние генетических факторов на длину теломер. Отдельно в работе рассматривается влияние курения на старение головного мозга и старение лица. Приводятся данные о важности своевременного прекращения курения с целью замедления темпов старения.

A narrative review was conducted to assess the impact of smoking on health and the rate of aging at different stages of a person’s life. The relationship between smoking and various markers of aging was considered in the review. Data from a Mendelian-type study that assessed the genetic predisposition to smoking and the length of telomeres were presented. The effect of smoking on brain aging and facial aging was analyzed separately. Provided data highlights the significance of timely smoking cessation in slowing down the rate of aging.

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The authors declare that there are no conflicts of interest present.