Mild behavioral impairment as a predictor of cognitive decline in old age
https://doi.org/10.37586/2949-4745-2-2025-76-84
Abstract
More and more researchers in the field of neurodegenerative diseases are paying attention to non-cognitive manifestations that arise in old age. Their role is actively debated: whether they act as factors increasing the likelihood of developing severe cognitive impairment or represent early manifestations of the condition's first signs. This review presents information on the incidence of mild behavioral impairments (MBI) in patients with subjective cognitive decline (SCD) and mild cognitive impairment (MCI), which are associated with an increased risk of developing dementia. MBI syndrome, which is currently used in conjunction with MCI, is described in detail. Mild behavioral impairments are a new strategy aimed at predicting the development of dementia even before the onset of cognitive symptoms. Data from international studies over the past ten years devoted to the study of the influence of MBI on cognitive decline are summarized. Issues of differential diagnosis of these disorders and the methods used to diagnose MBI are considered.
About the Author
N. N. Koberskaya
Faculty of General Medicine, Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) ; Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation (Pirogov University), Russian Gerontological Research and Clinical Center
Россия
Россия
Koberskaya Nadezhda Nikolaevna
Moscow
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Review
For citations:
Koberskaya N.N. Mild behavioral impairment as a predictor of cognitive decline in old age. Problems of Geroscience. 2025;(2):76-84. (In Russ.) https://doi.org/10.37586/2949-4745-2-2025-76-84
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